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Rehabilitation Physiology Lab


Osteoarthritis

ABSTRACTS

PREVIOUS GRANTS

NM Fisher (Principal Investigator, Faculty Preceptor for James Graham). Rheumatology-Related Health Professional Graduate Student Research Preceptorship for "Effects of Resistance Training on Strength, Endurance and EMG Activity in Individuals with Knee Osteoarthritis". American College of Rheumatology Research and Education Foundation. $4,000, 7/02-9/02.

DR Pendergast, GE Gresham and NM Fisher (Project Director). Progressive Quantitative Exercise in Arthritis of the Knees. National Institute of Disability and Rehabilitation Research, US Department of Education, #H133A80002, $501,597, 1988-1991.

PUBLISHED ABSTRACTS

Fisher NM. Effects of Three Exercise Rehabilitation Programs on the Relationship between Muscular Strength and Efficiency in Knee Osteoarthritis. Arthritis Rheum 52(9)Suppl:S434, 2005.

Fisher NM
, DM Dolan, C Brenner, DR Pendergast. Quantitative Effects of a Water Exercise Program on Functional and Physiological Capacity in Subjects with Osteoarthritis: a Pilot Study. Sport Sciences for Health 1(1):17-24, 2004

Graham J, N Fisher. Effects of Resistance Training on Muscle Function in Individuals with Knee Osteoarthritis. Arthritis & Rheumatism 48(9) suppl: S445, 2003.

Fisher NM and DR Pendergast. Reduced Muscle Function in Patients with Osteoarthritis . Scand J Rehab Med 29:213-221, 1997.

Fisher NM, SC White, HJ Yack, RJ Smolinski and DR Pendergast. Muscle Function and Gait in Patients with Knee Osteoarthritis before and after Muscle Rehabilitation. Disability Rehabil 19(2):47-55, 1997.

Fisher NM and DR Pendergast. Application of Quantitative and Progressive Exercise Rehabilitation to Patients with Osteoarthritis of the Knee . Journal of Back and Musculoskeletal Rehabilitation 5:33-53, 1995.

Fisher NM and DR Pendergast. Effects of a Muscle Exercise Program on Exercise Capacity in Subjects with Osteoarthritis . Arch Phys Med Rehabil 75(7):792-797, 1994.

Fisher NM, VD Kame, L Rouse and DR Pendergast. Quantitative Evaluation of a Home Exercise Program on Muscle and Functional Capacity of Patients with Osteoarthritis. Am J Phys Med Rehabil 73:413-420, 1994.

Fisher NM, GE Gresham and DR Pendergast. Quantitative Progressive Exercise Rehabilitation (QPER) for Osteoarthritis of the Knee . Physical Medicine and Rehabilitation Clinics of North America 5(4):785-802, 1994.

Leddy JJ, NM Fisher, RJ Smolinski, YK Barodawala, P Pandya and DR Pendergast. Effects of Exercise Rehabilitation on Muscle Function, Activity and Joint Spaces in Patients with Osteoarthritis. Med Sci Sports Exerc 26(suppl):S142, 1994.

Fisher NM, GE Gresham and DR Pendergast. Effects of a quantitative progressive rehabilitation program applied unilaterally to the osteoarthritic knee. Arch Phys Med Rehabil 74(12):1319-1326, 1993.

Fisher NM, GE Gresham, M Abrams, J Hicks, D Horrigan and DR Pendergast. Quantitative effects of physical therapy on muscular and functional performance in subjects with osteoarthritis of the knees . Arch Phys Med Rehabil 74(8):840-847, 1993.

Fisher NM, SC White, JH Yack, RJ Smolinski and DR Pendergast. Muscle Function and Gait in Patients with Knee Osteoarthritis before and after Muscle Rehabilitation. Arch Phys Med Rehabil 73(10):972, 1992.

Fisher NM, DR Pendergast, GE Gresham and E Calkins. Muscle rehabilitation: its effect on muscular and functional performance of patients with knee osteoarthritis . Arch Phys Med Rehabil 72(6):367-374, 1991.

Pendergast DR, VD Kame Jr, L Rouse and NM Fisher. Quantitative Evaluation of a Physical Therapy Supervised Home Exercise Program on Muscle and Functional Capacity of Patients with Osteoarthritis. Arch Phys Med Rehabil 72:792, 1991.

Fisher NM, VD Kame Jr and DR Pendergast. Effects of Muscle Rehabilitation on Cardiovascular Fitness in Patients with Osteoarthritis. Gerontologist 31(Special Issue II):9, 1991.

Maximal aerobic power has been shown to decrease with age and to be even lower in patients with osteoarthritis (OA). Patients with OA have also been shown to have reduced muscle function. The purpose of the present study was to determine if patients with OA who underwent only muscle rehabilitation had improved cardiovascular fitness. The subjects were given a maximal graded exercise test prior to and after 3 months of muscle rehabilitation. The exercise program consisted of isometric, isotonic, and endurance knee flexion and extension contractions, 3 times per week. Maximal strength and endurance improved significantly with this protocol. Maximal aerobic power increased from 13.0 +/- 2.5 ml/kg to 20.0 +/- 4.0 ml/kg, while maximal walking speed increased from 2.5 mph to 3.0 mph and exercise time increased from 9.3 +/- 1.5 minutes to 14.3 +/- 3.2 minutes. Although maximal heart rate and systolic blood pressure (SBP) did not increase, the heart rate (15 b/min) and SBP (20 mm Hg) at specific V02s was less. It would appear that the reduction in aerobic fitness of patients with OA is secondary to their reduced muscle function, and can be improved through muscle rehabilitation.


Fisher NM, DR Pendergast and GE Gresham. Reduced Muscle and Functional Performance in Patients with Osteoarthritis. Arch Phys Med Rehabil 71:783, 1990.

Fisher NM, DR Pendergast and GE Gresham. Progressive Quantitative Rehabilitation of Patients with Osteoarthritis. Arch Phys Med Rehabil 71:762, 1990.


Book Chapters

Fisher NM. Chapter 10: Osteoarthritis Rheumatoid Arthritis, and Fibromyalgia. ACSM's Resources for Clinical Exercise Physiology: Musculoskeletal, Neuromuscular, Neoplastic, Immunologic, and Hematologic Conditions. JN Meyers, WG Herbert, R Humphrey (Eds). Lippincott Williams & Wilkins: Baltimore, pgs. 111-124, 2002.

Fisher NM and DR Pendergast. Chapter 16: Quantitative Progressive Exercise Rehabilitation (QPER): Rehabilitation of Patients with Osteoarthritis. In: Key Aspects of Caring for the Chronically Ill. Hospital and Home. SG Funk, EM Tornquist, MT Champagne and RA Wiese (Eds). Springer Publishing Co., pgs. 178-189, 1993.









 



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