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Rehabilitation Physiology Lab


Fisher NM, DR Pendergast and GE Gresham. Reduced Muscle and Functional Performance in Patients with Osteoarthritis. Arch Phys Med Rehabil 71:783, 1990.

Osteoarthritis (OA) is one of the most prevalent diseases in the elderly. It was our hypothesis that OA leads to reduced function of muscles about the knee. Fifty-nine patients with OA were compared to 54 age-matched and sex-matched controls (age = 64.6 +/- 1.9 years and 65.0 +/- 0.4 years, respectively). Walking time (50') was 40% slower in patients with OA (10.8 +/- 0.6 sec). Dependency (1.24 +/- .04), difficulty (2.14 +/- .11), and pain (1.72 +/- .08), assessed by the Jette Functional Status Index, were 50% greater for OA patients. Maximal isometric strength of knee extension was 10.4 +/- 1.2, 13.5 +/- 1.5, 14.0 +/- 0.6, 14.0 +/- 1.6, 13.3 +/- 1.5Kg at hip angles of 45 degrees, 90 degrees, 120 degrees, 150 degrees, and 180 degrees respectively. The force-time integral for isometric knee extension to failure were 674 +/- 64, 658 +/- 81, and 727 +/- 90Kg sec at knee angles of 60 degrees, 90 degrees, and 135 degrees, respectively. Maximal velocities of muscle shortening during knee extension were 149 +/- 9, 141 +/- 9, 140 +/- 10, and 133 +/- 11 degrees/sec for resistances of 1 to 5Kg, respectively. OA patients had less muscular strength (50%), endurance (50%), and contraction velocities (60%) than controls (p<.05, ANOVA). Patients with OA have equal reductions in muscle function and functional performance (50%). (Supported by NIDRR #H133A-80002).

 

OTHER ABSTRACTS

Fisher NM. Effects of Three Exercise Rehabilitation Programs on the Relationship between Muscular Strength and Efficiency in Knee Osteoarthritis. Arthritis Rheum 52(9)Suppl:S434, 2005.

Fisher NM
, DM Dolan, C Brenner, DR Pendergast. Quantitative Effects of a Water Exercise Program on Functional and Physiological Capacity in Subjects with Osteoarthritis: a Pilot Study. Sport Sciences for Health 1(1):17-24, 2004

Graham J, N Fisher. Effects of Resistance Training on Muscle Function in Individuals with Knee Osteoarthritis. Arthritis & Rheumatism 48(9) suppl: S445, 2003.

Fisher NM and DR Pendergast. Reduced Muscle Function in Patients with Osteoarthritis . Scand J Rehab Med 29:213-221, 1997.

Fisher NM, SC White, HJ Yack, RJ Smolinski and DR Pendergast. Muscle Function and Gait in Patients with Knee Osteoarthritis before and after Muscle Rehabilitation. Disability Rehabil 19(2):47-55, 1997.

Fisher NM and DR Pendergast. Application of Quantitative and Progressive Exercise Rehabilitation to Patients with Osteoarthritis of the Knee . Journal of Back and Musculoskeletal Rehabilitation 5:33-53, 1995.

Fisher NM and DR Pendergast. Effects of a Muscle Exercise Program on Exercise Capacity in Subjects with Osteoarthritis . Arch Phys Med Rehabil 75(7):792-797, 1994.

Fisher NM, VD Kame, L Rouse and DR Pendergast. Quantitative Evaluation of a Home Exercise Program on Muscle and Functional Capacity of Patients with Osteoarthritis. Am J Phys Med Rehabil 73:413-420, 1994.

Fisher NM, GE Gresham and DR Pendergast. Quantitative Progressive Exercise Rehabilitation (QPER) for Osteoarthritis of the Knee . Physical Medicine and Rehabilitation Clinics of North America 5(4):785-802, 1994.

Leddy JJ, NM Fisher, RJ Smolinski, YK Barodawala, P Pandya and DR Pendergast. Effects of Exercise Rehabilitation on Muscle Function, Activity and Joint Spaces in Patients with Osteoarthritis. Med Sci Sports Exerc 26(suppl):S142, 1994.

Fisher NM, GE Gresham and DR Pendergast. Effects of a quantitative progressive rehabilitation program applied unilaterally to the osteoarthritic knee. Arch Phys Med Rehabil 74(12):1319-1326, 1993.

Fisher NM, GE Gresham, M Abrams, J Hicks, D Horrigan and DR Pendergast. Quantitative effects of physical therapy on muscular and functional performance in subjects with osteoarthritis of the knees . Arch Phys Med Rehabil 74(8):840-847, 1993.

Fisher NM, SC White, JH Yack, RJ Smolinski and DR Pendergast. Muscle Function and Gait in Patients with Knee Osteoarthritis before and after Muscle Rehabilitation. Arch Phys Med Rehabil 73(10):972, 1992.

Fisher NM, DR Pendergast, GE Gresham and E Calkins. Muscle rehabilitation: its effect on muscular and functional performance of patients with knee osteoarthritis . Arch Phys Med Rehabil 72(6):367-374, 1991.

Pendergast DR, VD Kame Jr, L Rouse and NM Fisher. Quantitative Evaluation of a Physical Therapy Supervised Home Exercise Program on Muscle and Functional Capacity of Patients with Osteoarthritis. Arch Phys Med Rehabil 72:792, 1991.

Fisher NM, VD Kame Jr and DR Pendergast. Effects of Muscle Rehabilitation on Cardiovascular Fitness in Patients with Osteoarthritis. Gerontologist 31(Special Issue II):9, 1991.

Fisher NM, DR Pendergast and GE Gresham. Progressive Quantitative Rehabilitation of Patients with Osteoarthritis. Arch Phys Med Rehabil 71:762, 1990.

Gresham GE, NM Fisher, DR Pendergast and E Calkins. Quantitative Quadriceps Strengthening in Osteoarthritis of the Knees. Arch Phys Med Rehabil 69:725, 1988.