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Rehabilitation Physiology Lab


Fisher NM and DR Pendergast. Effects of a Muscle Exercise Program on Exercise Capacity in Subjects with Osteoarthritis . Arch Phys Med Rehabil 75(7):792-797, 1994.

Maximal aerobic power and muscle function have been shown to decrease with age and to be even lower in patients with osteoarthritis (OA). This study was designed to determine if subjects with OA who underwent only a muscle exercise program had improved exercise capacity and cardiovascular fitness. A maximal graded exercise test was given before and after 3 months of exercise (isometric, isotonic, and isometric force generated as a function of time contractions, three times a week). Maximal strength and the tension-time index improved significantly. Peak aerobic power increased from 15.99 + 3.96mL kg-1 min-1 to 20.34 + 3.29mL kg-1 min-1. On average, maximal walking speed increased from 2.0 + 0.6mph to 2.4 + 0.7mph. Exercise time increased 22%, from 9.2 + 2.3 minutes to 11.2 + 2.7 minutes. there were significant reductions in submaximal heart rate (15b min-1) and systolic blood pressure (15mmHg) after training. It would appear that the reduction in aerobic fitness of subjects with OA is secondary to their reduced muscle function. By improving muscle function, increases in exercise capacity and aerobic fitness occurred.

 

OTHER ABSTRACTS

Fisher NM. Effects of Three Exercise Rehabilitation Programs on the Relationship between Muscular Strength and Efficiency in Knee Osteoarthritis. Arthritis Rheum 52(9)Suppl:S434, 2005.

Fisher NM
, DM Dolan, C Brenner, DR Pendergast. Quantitative Effects of a Water Exercise Program on Functional and Physiological Capacity in Subjects with Osteoarthritis: a Pilot Study. Sport Sciences for Health 1(1):17-24, 2004

Graham J, N Fisher. Effects of Resistance Training on Muscle Function in Individuals with Knee Osteoarthritis. Arthritis & Rheumatism 48(9) suppl: S445, 2003.

Fisher NM and DR Pendergast. Reduced Muscle Function in Patients with Osteoarthritis . Scand J Rehab Med 29:213-221, 1997.

Fisher NM, SC White, HJ Yack, RJ Smolinski and DR Pendergast. Muscle Function and Gait in Patients with Knee Osteoarthritis before and after Muscle Rehabilitation. Disability Rehabil 19(2):47-55, 1997.

Fisher NM and DR Pendergast. Application of Quantitative and Progressive Exercise Rehabilitation to Patients with Osteoarthritis of the Knee . Journal of Back and Musculoskeletal Rehabilitation 5:33-53, 1995.

Fisher NM, VD Kame, L Rouse and DR Pendergast. Quantitative Evaluation of a Home Exercise Program on Muscle and Functional Capacity of Patients with Osteoarthritis. Am J Phys Med Rehabil 73:413-420, 1994.

Fisher NM, GE Gresham and DR Pendergast. Quantitative Progressive Exercise Rehabilitation (QPER) for Osteoarthritis of the Knee . Physical Medicine and Rehabilitation Clinics of North America 5(4):785-802, 1994.

Leddy JJ, NM Fisher, RJ Smolinski, YK Barodawala, P Pandya and DR Pendergast. Effects of Exercise Rehabilitation on Muscle Function, Activity and Joint Spaces in Patients with Osteoarthritis. Med Sci Sports Exerc 26(suppl):S142, 1994.

Fisher NM, GE Gresham and DR Pendergast. Effects of a quantitative progressive rehabilitation program applied unilaterally to the osteoarthritic knee. Arch Phys Med Rehabil 74(12):1319-1326, 1993.

Fisher NM, GE Gresham, M Abrams, J Hicks, D Horrigan and DR Pendergast. Quantitative effects of physical therapy on muscular and functional performance in subjects with osteoarthritis of the knees . Arch Phys Med Rehabil 74(8):840-847, 1993.

Fisher NM, SC White, JH Yack, RJ Smolinski and DR Pendergast. Muscle Function and Gait in Patients with Knee Osteoarthritis before and after Muscle Rehabilitation. Arch Phys Med Rehabil 73(10):972, 1992.

Fisher NM, DR Pendergast, GE Gresham and E Calkins. Muscle rehabilitation: its effect on muscular and functional performance of patients with knee osteoarthritis . Arch Phys Med Rehabil 72(6):367-374, 1991.

Pendergast DR, VD Kame Jr, L Rouse and NM Fisher. Quantitative Evaluation of a Physical Therapy Supervised Home Exercise Program on Muscle and Functional Capacity of Patients with Osteoarthritis. Arch Phys Med Rehabil 72:792, 1991.

Fisher NM, VD Kame Jr and DR Pendergast. Effects of Muscle Rehabilitation on Cardiovascular Fitness in Patients with Osteoarthritis. Gerontologist 31(Special Issue II):9, 1991.

Fisher NM, DR Pendergast and GE Gresham. Reduced Muscle and Functional Performance in Patients with Osteoarthritis. Arch Phys Med Rehabil 71:783, 1990.

Fisher NM, DR Pendergast and GE Gresham. Progressive Quantitative Rehabilitation of Patients with Osteoarthritis. Arch Phys Med Rehabil 71:762, 1990.

Gresham GE, NM Fisher, DR Pendergast and E Calkins. Quantitative Quadriceps Strengthening in Osteoarthritis of the Knees. Arch Phys Med Rehabil 69:725, 1988.